University of Iowa Stead Family Department of Pediatrics Division of Hematology/Oncology is seeking a Research Assistant who will be responsible for maintaining the laboratory and performing research related activities within the Stead Family Department of Pediatrics, Division of Hematology/Oncology. This position will provide support by conducting hematology experiments, collecting and analyzing results and performing operation duties related to hemostasis and thrombosis.
It is expected that as the research assistant gains experience with laboratory techniques and procedures, they will take on increased autonomy and collaboration with other laboratory members. They will also gradually increase the scientific level of their duties by adding experimental design and data analysis as well as preparation of materials for abstracts/reports/grant applications and manuscripts.
This is a specified term position.
University of Iowa Stead Family Department of Pediatrics is a national leader in pediatric medicine. The Departments mission is to provide outstanding care to the children of Iowa and beyond by being a leader in state-of-the-art clinical care to children, performing cutting-edge research to find new treatments and cures for childhood illnesses, and educating the next generation of pediatric health care providers. The Department comprises the medical and research staff of UI Stead Family Childrens Hospital. UI Stead Family Childrens Hospital is one of the nations top-ranked pediatric care and research institutions, and Iowas only comprehensive childrens hospital.
The division of Pediatric Hematology/Oncology at UI Childrens Hospital is a pioneer in the care and treatment of childhood cancers and blood disorders. It is part of the Holden Comprehensive Cancer Center, and a member of the Childrens Oncology Group (COG), a national consortium of pediatric cancer centers. The COG is well known for its new and innovative ways of treating childhood cancer. The division has a long history of success in bringing hope to patients with programs such as our blood and bone marrow transplant, comprehensive sickle cell program, and comprehensive hemophilia center. The mission of the division is to treat and cure children and adolescents with cancer and blood diseases who live in Iowa by delivering personalized multidisciplinary, state-of-the-art care, through participation both in nationally and locally designed protocols.
Duties to include:
- Perform research activities based upon protocols developed by other research staff or principal investigator of the research project.
- As individual skills develop, analyze literature to develop hypothesis for discussion with other researchers or principal investigator.
Collect, Analyze and Summarize Data; Prepare Reports; Contribute to Manuscripts, Publications
- Present results at lab meetings.
- Prepare figures and methods for use in posters, manuscripts, and grant applications.
- Prepare bibliographies and abstracts according to instructions.
- Collect, track, and perform data entry for reports. Prepare materials for reports to be written by faculty and staff on the research project.
Experiments, Investigations, Evaluations
- Plan and perform experimental procedures assuring fidelity to protocols; record and analyze data
- Perform research activities related to the analysis of coagulationi assays including platelet studies.
- Develop, troubleshoot and analyze experimental protocols; propose modifications to other researchers or principal investigator; design new protocols with assistance from other researchers or principal investigator
- Perform animal experiments including handling, weighing, and restraining mice, administering various injections including subcutaneous, intraperitoneal, and tail vein; performing mouse euthanasia; perform blood draws; and harvest tissues on euthanized mice. Maintain mouse colony records.
- Perform cloning; Perform DNA, RNA and protein based studies of gene expression; construction and production of viral and non-viral vectors. Perform gene expression studies on cells and tissues.
- Perform immunohistochemistry and immunofluorescent studies
- Operate light microscopes and acquire microscopic imaging data including confocal.
- Perform complex techniques as outlined in research protocols and test and evaluate current procedures.
Project Preparation and Equipment
- With minimal help from PI, arrange and plan daily activities to prepare for and perform experiments
- Arrange and plan weekly to monthly activities to prepare for and perform experiments, with minimal help from PI and other investigators.
- Read and understand protocols.
- Troubleshoot and analyze protocols; propose modifications to other researchers or principal investigator; develop and monitor quality controls..
- Perform experimental procedures assuring fidelity to protocols; record and consolidate data as directed by Principal Investigator (PI).
- Track progress/success of research project.
- Obtain subject consent and assist with IRB submissions or equivalent protocol, if applicable.
- May initiate purchasing requests, monitor accounts/expenditures; reconcile statements
- Assist with procurement of supplies and materials.
- Develop and monitor quality control testing of equipment as necessary
- Assist in the preparation, calibration, and maintenance of laboratory and facility equipment.
- Adhere to safety and compliance guidelines
Percent of Time:
Pay Grade: 3A
- Regular salaried position located in Iowa City, Iowa
- Fringe benefit package including paid vacation; sick leave; health, dental, life and disability insurance options; and generous employer contributions into retirement plans
- For more information about Why Iowa?, click here
- A Bachelors degree in a natural or health science field or discipline, or an equivalent combination of education and experience.
- Minimum of one year of prior research experience in a related field.
- Demonstrated experience with data entry and managing research databases according to best practice.
- Demonstrated experience in molecular biology techniques.
- Ability to work well both independently and in a team setting.
- Excellent in organizational skills with attention to detail.
- Excellent written and verbal communication and interpersonal skills.
- Demonstrated commitment to promoting a diverse, equitable and inclusive work environment.
Highly Desired Qualifications
- Demonstrated experience in hematology/hemostasis/thrombosis.
- Experience using in vector/gene therapy studies, tissue sectioning and immunohistochemistry.
- Minimum of one year experience caring for and handling mice to include mouse colony maintenance and management is highly desired.
- Experience arranging and planning weekly to monthly activities to prepare for and perform experiments.
- Experience performing experimental procedures assuring fidelity to protocols; record and consolidate data as directed by Principal Investigator (PI).
In order to be considered, applicants must upload
Resume and Cover Letter
(under submission relevant materials) that clearly address how they meet the listed required and desired qualifications of this position.
Job openings are posted for a minimum of 14
calendar days and may be removed from posting and filled at any time after the orignial posting period has ended.
Successful candidates will be subject to a criminal background check. This position is not eligible for University sponsorship for employment authorization.
- Classification Title: Research Assistant
- Appointment Type: Professional and Scientific
- Schedule: Full-time
- Organization: Healthcare
- Contact Name: *****/li>
- Contact Email: *****/li>