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Takeda Pharmaceuticals

Boston, MA

Immunological Assays Lead, Global Gene Therapy Biological Scientist Jobs in Boston, Massachusetts

Location444 E 3rd St, Boston, Massachusetts 02128
Employment TypeContractor
Date Posted2022-08-07
Direct Apply
Yes
Valid Through2023-06-26

Job Description:

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Job Description

Are you looking for a patient-focused company that enables transformative technologies to address patients' needs while inspiring you and support your career? Takeda is a world-class organization where we combine our expertise in disease biology, modality technologies and drug development experience to develop gene therapies in a holistic approach.

OBJECTIVES:

As one of the Immunological Assays lead in the Global Gene Therapy (GGT) Research Team, you will manage immunological assays that contribute to discovery research gene therapy (GT) projects in the research pipeline. You will support the immunological aspect of gene therapy in forward and reverse translation across multiple line functions to progress GT projects. You will report to the Head of Immunological Assays-Global Gene Therapy.

ACCOUNTABILITIES:

  • Independently or in collaboration with co-leads design, troubleshoot and execute immunological assays to support early research projects in GGT and/or in collaboration with other units.

  • Proficient in utilization of FACS, MSD, autoMACS, and executing ELISA, ELISPOT, ADA & Nab assays from multiple different species against the drug product or the transgene product.

  • Contribute and/or lead the development of immunoassays, immunophenotyping, PBMC isolation from human, mice and NHPs (T cell culture is required).

  • Responsible for appropriate data interpretations of the results conducted by the candidate or as part of the team.

  • Demonstrate excellent organizational and communication skills. Responsible for completion of experiments and deliverables within established timelines and great attention to details for Takeda's GT projects.

  • Identify novel technologies or improvements for immunoassays that will contribute to the progress of GT projects.

  • Follow compliance of documentations in electronic lab book and Takeda's internal documentation.

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS :

  • PhD degree in Immunology with 2+ years of experience, or

  • MS with 4+ years of experience, or

  • BS with 8+ years of experience

  • 2+ years of Industry experience

  • Minimum 5 years of relevant experience and hands-on performing several immunological assays, T cells culture, in vitro and in vivo models to evaluate immune responses.

  • Proficient in the use of FACS, MSD, autoMACS, and performing ELISA, ELISPOT, ADA &

  • Nab assays, PBMC isolation, T cells culture is required.

  • Experience troubleshooting assays development and QC of assays is very important.

  • Experience with writing assay protocol, electronic lab book, documentation and study reports that could contribute to regulatory filing documents.

Employees are eligible to participate in Medical, Dental. Vision, Life Insurance, 401(k), Charitable Contribution Match, Company Holidays, Personal & Vacation Days, Student Loan Repayment Program and Paid Volunteer Time Off.

Effective November 1, 2021, absent an approved religious or medical reason, all US office-based and lab-based Takeda employees who work fully on-site or in a hybrid model (as determined by Takeda) must be fully vaccinated to work at a Takeda site or to engage with Takeda colleagues or anyone else on behalf of Takeda. As of the same date, absent an approved religious or medical reason, US field-based employees, employees must be fully vaccinated in order to continue in their current roles. US employees who work at a Takeda manufacturing facility, and those who work at a BioLife center or BioLife lab, may be subject to different guidelines. Candidates are encouraged to speak with their recruiter to seek further information on the applicable guidelines for the Business Unit/Function for which they have applied.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Colorado applicants are excluded from this posting.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job ID: 7525927667540092158

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